Evolution in Tactics and Management of Complicated Diverticulitis: Our Experience with Minimally Invasive Techniques
DOI:
https://doi.org/10.14748/j04vpr72Keywords:
complicated diverticulosis, minimally invasive surgery, individualizedAbstract
Introduction: Over the past two decades, the interest in diverticular disease has increased significantly. For the first time, a rise in its incidence was described in the literature during the Industrial Revolution, when differences in prevalence between Western and Eastern populations were demonstrated—differences that persist to this day. The risk of a patient with diverticulosis developing diverticulitis is estimated at less than 5%. Diverticulitis, in turn, leads to complications in approximately 12% of cases. The most frequent complications are abscesses or phlegmons (about 70%), followed by peritonitis, obstruction, and fistula formation. Historically, laparotomy with resection of the affected colonic segment was considered the cornerstone in the treatment of complicated diverticulitis; however, in recent years, it has largely been replaced by less invasive and less aggressive therapeutic approaches.
Aim: The aim of our study was to analyze the outcomes of treating complicated forms of diverticulitis through the use of minimally invasive methods.
Materials and Methods: We reviewed a 13-year period (May 2012–May 2025) of patients treated for complicated diverticular disease at the Department of Surgery, Eurohospital University Hospital, Plovdiv. During this period, 208 patients were treated. In 72 cases, diverticular perforation with varying degrees of infectious spread was identified. Non-operative management was applied in 11 cases, including antibiotic therapy, dietary regimen, and percutaneous drainage. Emergency surgery was required in 61 patients.
Results: Of the 61 surgically treated patients, 35 underwent laparoscopic procedures (57.38%). The conversion rate was 8.57% (3 cases). The remaining 26 patients were treated conventionally (42.62%). Postoperative complications such as wound infections, stoma-related issues, and anastomotic leaks were documented and compared between the minimally invasive and open surgery groups. Patients in the laparoscopic group demonstrated shorter operative times, reduced hospital stay, and shorter duration of antibiotic use.
Conclusion: The management of acute diverticulitis has changed significantly in recent years due to modern diagnostic modalities and non-operative interventional methods. Careful patient selection, an individualized approach, and the application of minimally invasive surgery represent the preferred treatment strategy. Our study fully confirms the findings reported in the literature. The use of modern surgical techniques results in shorter hospital stays, reduced operative times, lower rates of postoperative complications, decreased overall treatment costs, and improved quality of life for patients.
References
[1] Cirocchi R, Arezzo A, Vettoretto N, et al. Role of damage control surgery in the treatment of Hinchey III and IV sigmoid diverticulitis: a tailored strategy. Medicine (Baltimore). 2014 Nov;93(25):e184. doi: 10.1097/MD.0000000000000184.
[2] Hupfeld L, Burcharth J, Pommergaard HC, et al. The best choice of treatment for acute colonic diverticulitis with purulent peritonitis is uncertain. Biomed Res Int. 2014;2014:380607. doi: 10.1155/2014/380607.
[3] Lipman JM, Reynolds HL. Laparoscopic management of diverticular disease. Clin Colon Rectal Surg. 2009 Aug;22(3):173-80. doi: 10.1055/s-0029-1236162.
[4] Sartelli M, Moore FA, Ansaloni L, et al. A proposal for a CT driven classification of left colon acute diverticulitis. World J Emerg Surg. 2015 Feb 19;10:3. doi: 10.1186/1749-7922-10-3.
[5] Champagne BJ, Papaconstantinou HT, Parmar SS, et al. Single-incision versus standard multiport laparoscopic colectomy: a multicenter, case-controlled comparison. Ann Surg. 2012 Jan;255(1):66-9. doi: 10.1097/SLA.0b013e3182378442.
[6] Etzioni DA, Mack TM, Beart RW Jr, et al. Diverticulitis in the United States: 1998-2005: changing patterns of disease and treatment. Ann Surg. 2009 Feb;249(2):210-7. doi: 10.1097/SLA.0b013e3181952888.
[7] Bharucha AE, Parthasarathy G, Ditah I, et al. Temporal Trends in the Incidence and Natural History of Diverticulitis: A Population-Based Study. Am J Gastroenterol. 2015 Nov;110(11):1589-96. doi: 10.1038/ajg.2015.302.
[8] Elagili F, Stocchi L, Ozuner G, et al. Outcomes of percutaneous drainage without surgery for patients with diverticular abscess. Dis Colon Rectum. 2014 Mar;57(3):331-6. doi: 10.1097/DCR.0b013e3182a84dd2.
[9] Larach S. Laparoscopic management of diverticular disease. Clin Colon Rectal Surg. 2004 Aug;17(3):187-93. doi: 10.1055/s-2004-832701.
[10] Sandler RS, Everhart JE, Donowitz M, et al. The burden of selected digestive diseases in the United States. Gastroenterology. 2002 May;122(5):1500-11. doi: 10.1053/gast.2002.32978.
[11] Devaraj B, Liu W, Tatum J, et al. Medically Treated Diverticular Abscess Associated With High Risk of Recurrence and Disease Complications. Dis Colon Rectum. 2016 Mar;59(3):208-15. doi: 10.1097/DCR.0000000000000533.
[12] Delvaux M. Diverticular disease of the colon in Europe: epidemiology, impact on citizen health and prevention. Aliment Pharmacol Ther. 2003 Nov;18 Suppl 3:71-4. doi: 10.1046/j.0953-0673.2003.01720.x.
[13] Abbas MA, Cannom RR, Chiu VY, et al. Triage of patients with acute diverticulitis: are some inpatients candidates for outpatient treatment? Colorectal Dis. 2013 Apr;15(4):451-7. doi: 10.1111/codi.12057.
[14] Park HC, Kim BS, Lee BH. Management of right colonic uncomplicated diverticulitis: outpatient versus inpatient management. World J Surg. 2011 May;35(5):1118-22. doi: 10.1007/s00268-011-1048-0.
[15] Ribas Y, Bombardó J, Aguilar F, et al. Prospective randomized clinical trial assessing the efficacy of a short course of intravenously administered amoxicillin plus clavulanic acid followed by oral antibiotic in patients with uncomplicated acute diverticulitis. Int J Colorectal Dis. 2010 Nov;25(11):1363-70. doi: 10.1007/s00384-010-0967-9.
[16] Chabok A, Påhlman L, Hjern F, et al. Randomized clinical trial of antibiotics in acute uncomplicated diverticulitis. Br J Surg. 2012 Apr;99(4):532-9. doi: 10.1002/bjs.8688.
[17] Westwood DA, Eglinton TW. Antibiotics may not improve short-term or long-term outcomes in acute uncomplicated diverticulitis. Evid Based Med. 2013 Feb;18(1):32-3. doi: 10.1136/eb-2012-100762.
[18] Oberkofler CE, Rickenbacher A, Raptis DA, et al. A multicenter randomized clinical trial of primary anastomosis or Hartmann's procedure for perforated left colonic diverticulitis with purulent or fecal peritonitis. Ann Surg. 2012 Nov;256(5):819-26; discussion 826-7. doi: 10.1097/SLA.0b013e31827324ba.
[19] Klarenbeek BR, Veenhof AA, Bergamaschi R, et al. Laparoscopic sigmoid resection for diverticulitis decreases major morbidity rates: a randomized control trial: short-term results of the Sigma Trial. Ann Surg. 2009 Jan;249(1):39-44. doi: 10.1097/SLA.0b013e31818e416a.
[20] Swank HA, Vermeulen J, Lange JF, et al. The ladies trial: laparoscopic peritoneal lavage or resection for purulent peritonitis and Hartmann's procedure or resection with primary anastomosis for purulent or faecal peritonitis in perforated diverticulitis (NTR2037). BMC Surg. 2010 Oct 18;10:29. doi: 10.1186/1471-2482-10-29.
[21] Schultz JK, Yaqub S, Wallon C, et al. Laparoscopic Lavage vs Primary Resection for Acute Perforated Diverticulitis: The SCANDIV Randomized Clinical Trial. JAMA. 2015 Oct 6;314(13):1364-75. doi: 10.1001/jama.2015.12076.
[22] Vennix S, Musters GD, Mulder IM, et al. Laparoscopic peritoneal lavage or sigmoidectomy for perforated diverticulitis with purulent peritonitis: a multicentre, parallel-group, randomised, open-label trial. Lancet. 2015 Sep 26;386(10000):1269-77. doi: 10.1016/S0140-6736(15)61168-0.
[23] Piccolini M, Francia L, Rosa C, et al. La malattia diverticolare complicata del colon: esperienza di 5 anni in un ospedale di provincia [Complicated diverticular disease of the colon: 5 years' experience in a provincial hospital]. Chir Ital. 2007 Mar-Apr;59(2):197-206. Italian.